Coordinators: Fabien Zoulim, Patrice Marche
Cancers caused by or linked with infections account for 15 to 20% of cancers worldwide, thus making them a major public health concern.
This involves in particular liver cancer, with the hepatitis B (HBV) and C (HCV) viruses; cervical cancer, with human papillomavirus (HPV); lymphoma, with Epstein-Barr virus (EBV); leukemia, with human T-cell lymphotrophic virus (HTLV-1); Kaposi’s Sarcoma, with human herpesvirus 8 (HHV8); and gastric cancer, caused by the Helicobacter pylori (H. pylori) bacterial strain.
Two themes have been specified for this focus area:
- Immune response in cancers and infections;
- Molecular mechanisms involved in cancer transformation.
There will also be cross-disciplinary programs aiming to develop diagnostic and therapeutic applications for cancer prevention and treatment.